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'One for the Road' brought beloved series to an end in 1993.

Alley also starred in ‘Look Who’s Talking’ and ‘Star Trek II.’

With Shelley Long's Diane gone, hit show brought in replacement to annoy Ted Danson's bar owner.

Start tossing the salads and scrambling the eggs.

Here’s a look at a handful of the best rivalries that have come down the pike on the small screen:

The marriage of Danny Devito and Rhea Perlman lasted for 30 years. By Hollywood standards, that is a century.